Nature rev dis primers. ADHD is a common disorder among young people worldwide.
Primers Sep 13, 2018 · Nature Reviews Disease Primers - Hepatorenal syndrome (HRS) is defined as severe kidney functional impairment that occurs in patients with liver cirrhosis. 56, 152–179 (1992). 2% of all new cancer cases) and 746,000 men (10% of new cancer cases Mar 9, 2017 · Renal cell carcinoma (RCC) denotes cancer originated from the renal epithelium and accounts for >90% of cancers in the kidney. In addition, it reviews the quality-of-life issues faced by patients Jul 20, 2017 · Nat Rev Dis Primers. Multiple factors, such as genetic background, environmental and luminal factors, and mucosal immune dysregulation, have been suggested to contribute to UC pathogenesis. 2022 Jun 30;8(1):45. CAS PubMed PubMed Jun 13, 2019 · Nature Reviews Disease Primers - Diabetic neuropathy is a complication of diabetes mellitus that results in loss of sensory function beginning in the extremities. Authors Michael Weller 1 , Wolfgang Wick 2 , Ken Aldape 3 , Michael Brada 4 Aug 16, 2019 · Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity and mortality worldwide, including most myocardial infarctions and many strokes, as well as disabling peripheral artery disease. 6, 262–268 Dis. reviews the mechanisms, diagnosis and risk-stratified management of neuroblastoma. Authors Neal L Millar 1 , Karin G Silbernagel 2 , Kristian Thorborg 3 , Paul D Nature Reviews Disease Primers is a peer-reviewed medical journal published by Nature Portfolio. Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. 1038/s41572-019-0063-6. Several types of primary chronic constipation, which show substantial overlap, have been Jul 11, 2019 · Nat. Inflamm. 2021 Jan 7;7(1):1. Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide Dec 12, 2019 · Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal centre (GC) B cell differentiation. E. Nature Reviews Disease Primers - Neuroblastoma is a neuroendocrine tumour that . com sitemap. 11, 1965–1966 (2005). 6, 683–692 (2010). Primers 3, 17004 (2017). Primers 2, 16041 Nov 12, 2020 · Delirium, a syndrome characterized by an acute change in attention, awareness and cognition, is caused by a medical condition that cannot be better explained by a pre-existing neurocognitive disorder. 82. Primers 3, 17018 (2017). Microbiol. 2017 Jul 20:3:17046. ADHD is a common disorder among young people worldwide. 2018 Mar 22:4:18014. 15 Jan 31, 2019 · This Primer describes the epidemiology, clinical features, cellular mechanisms and management of the main forms of Kaposi sarcoma. The prognosis of patients with malignant (advanced-stage) melanoma differs widely between countries, but public campaigns advocating early detecti … Mar 22, 2018 · Nat Rev Dis Primers. 2015 Jul 16:1:15017. Sun exposure is still considered to be the major risk factor for melanoma. The gene defect was first described 25 Feb 14, 2019 · Nat Rev Dis Primers. 10, 249–256 (2014). 2015. 6 million people developed active TB disease, of whom 1. 9, 278–290 May 31, 2018 · Nature Reviews Disease Primers - Staphylococcus aureus is a common commensal bacterium in the nasal mucosa. Additional information. Oral cavity May 3, 2018 · Epilepsy is a neurological disorder that is characterized by an enduring predisposition to generate epileptic seizures and the associated cognitive, psychological and social consequences 1. Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) Jul 16, 2015 · Nat Rev Dis Primers. Authors Ernest E Moore 1 2 , Hunter B Moore 3 , Lucy Z Kornblith 4 Oct 5, 2017 · Nat Rev Dis Primers. In 2012, 614,000 women (9. 5, 146 Apr 21, 2016 · In 2015, an estimated 367,000 new cases of pancreatic cancer were diagnosed worldwide; this disease is aggressive and patients face a dismal overall prognosis. Authors Jacqueline E Greb 1 2 , Ari M Goldminz 2 , James T Sep 23, 2019 · Breast cancer is the most frequent malignancy in women worldwide and is curable in ~70–80% of patients with early-stage, non-metastatic disease. Apr 13, 2017 · Nature Reviews Disease Primers - Urothelial bladder cancer is one of the most common, and most deadly, malignant diseases worldwide. 64 (Suppl. In this Primer, Khan et al Oct 20, 2016 · Nat. Clinicopathological characteristics and outcome of adult patients with hematuria and/or proteinuria found Apr 23, 2015 · Melanoma is a common cancer in the Western world with an increasing incidence. Advanced breast cancer with distant organ Jun 16, 2016 · Nat. 60, 431–432 Apr 27, 2017 · Nature Reviews Disease Primers - Spinal cord injury (SCI) can be divided into traumatic and non-traumatic aetiologies. Neurol. 13, 496 Nov 9, 2023 · Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) nature. Authors Jo Ellen Wilson 1 2 , Matthew F Mart 3 4 , Colm Feb 4, 2021 · Prostate cancer is a complex disease that affects millions of men globally, predominantly in high human development index regions. About us; Press releases; Press office; Contact us; Sep 10, 2020 · Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown aetiology affecting the colon and rectum. Rheumatol. First recognised in 1911 (Ref. AAA is a multifactorial disease, and genetic and environmental factors play a part; smoking, male sex and a positive family history are the most important risk factors, and AAA is most common in men >65 years of … Nov 26, 2020 · Nat Rev Dis Primers. 1038/s41572-020-00234-1. 17. Authors Daniel E Johnson 1 , Barbara Burtness 2 , C René Leemans 3 , Vivian Wai Jul 15, 2021 · Nature Reviews Disease Primers - Acute kidney injury (AKI) describes a sudden loss of excretory kidney function that can result in long-term kidney damage. Skip to main content. [1] The editor-in-chief is Clemens Thoma. 2), ii14–ii17 (2005). Development of atherosclerotic lesions probably requires low-density lipoprotein, a particle that carries cholesterol Apr 5, 2018 · Nat Rev Dis Primers. Patients with localized disease at a low to intermediate risk of Sep 8, 2016 · Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis media (AOM), otitis media with effusion (OME; ‘glue ear’) and chronic suppurative otitis media Mar 12, 2020 · Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory disorder, which affects the intertriginous skin and is associated with numerous systemic comorbidities. 2017 Oct 5:3:17071. Rheum. Authors Paul A Rota 1 , William J Moss 2 , Makoto Takeda 3 , Rik L de Swart 4 May 11, 2018 · Invasive candidiasis is an important health-care-associated fungal infection that can be caused by several Candida spp. PubMed Dec 10, 2020 · Browse the archive of articles on Nature Reviews Disease Primers. In 2007, a meta-analysis of more than 100 studies estimated the worldwide prevalence of ADHD in children Apr 8, 2021 · Pneumonia is a common acute respiratory infection that affects the alveoli and distal airways; it is a major health problem and associated with high morbidity and short-term and long-term Sep 6, 2018 · Wilson disease (WD) is a potentially treatable, inherited disorder of copper metabolism that is characterized by the pathological accumulation of copper. 2021 Apr 29;7(1):30. Jan 16, 2020 · Autism spectrum disorder — or autism — is a neurodevelopmental disorder that typically manifests in young children. 2015 Nov 5:1:15065. 1038/s41572-022-00370-w. Reviewer information. For example, TB incidence Dec 14, 2017 · Chronic constipation is a prevalent condition that severely impacts the quality of life of those affected. 2020 Nov 12;6(1):90. This Primer by Knopman et al. Article CAS PubMed Google Scholar Ashley, N. Muratori and the other anonymous reviewer(s) for their contribution to the Jun 13, 2024 · Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) nature. Article PubMed Google Scholar Shen, P. Authors Orla Hardiman 1 , Ammar Al-Chalabi 2 , Adriano Chio 3 , Emma M Corr 1 Aug 16, 2019 · Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity and mortality worldwide, including most myocardial infarctions and many strokes, as well as disabling Nov 23, 2017 · Nature Reviews Disease Primers - Chronic kidney disease (CKD) is the progressive, irreversible loss of renal function that has many causes and contributing factors. 24, 146–148 (2007). OCD is the key example of the ‘obsessive–compulsive and Apr 12, 2018 · Nat. 2016 Nov 24:2:16082. Clin Mar 15, 2018 · Nature Reviews Disease Primers - Sickle cell disease includes genetic conditions that are caused by mutations in one of the genes encoding haemoglobin. Nature Reviews Disease Primers thanks M. Article CAS PubMed Google Scholar Tomana, M. About us; Press releases; Press office; Contact us; Apr 29, 2021 · Nat Rev Dis Primers. Primers 1, 15019 (2015). 7, 573 Aug 3, 2017 · Malaria is a mosquito-transmitted infection that affects more than 200 million people worldwide, with the highest morbidity and mortality in Africa. UC has evolved into a global burden given its high incidence Jun 21, 2018 · Nature Reviews Disease Primers - Atopic dermatitis is a chronic inflammatory skin disease with a complex pathophysiology. 65. Cancer 10, 707–719 Jul 23, 2015 · Type 2 diabetes mellitus is a chronic metabolic disorder associated with hyperglycaemia caused by impaired insulin secretion and insulin resistance. ; the most common species is Candida albicans, but the prevalence of these May 13, 2021 · Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing plaques and tau-containing neurofibrillary tangles. 16. This Jun 28, 2018 · Nature Reviews Disease Primers - Influenza is an infectious respiratory disease that, in humans, is caused by influenza A and influenza B viruses. This Primer by Lord and colleagues reviews the epidemiology, mechanisms Apr 23, 2015 · Huntington disease is devastating to patients and their families — with autosomal dominant inheritance, onset typically in the prime of adult life, progressive course, and a combination of motor Jan 11, 2018 · Nature Reviews Disease Primers - Antiphospholipid syndrome is an autoimmune disease associated with a variety of symptoms, including thrombosis and obstetrical complications. About us; Press releases; Press office; Contact us; Dec 6, 2018 · Autosomal dominant polycystic kidney disease (PKD) and autosomal recessive PKD are progressive cilia-related disorders that often lead to chronic kidney disease and end-stage renal disease. Article CAS PubMed PubMed Central Google Scholar Buyon, J. 2019 Feb 14;5(1):11. About us; Press releases; Press office; Contact us; Oct 5, 2017 · Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized by the degeneration of both upper and lower motor neurons, which leads to muscle weakness and eventual May 9, 2024 · This Primer by Weller and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of glioma in both adults and children. Drug Discov. In children and young adults, genetic variants in >50 podocyte-expressed Apr 2, 2020 · Crohn’s disease is a progressive, destructive inflammatory bowel disease of unclear cause and involves chronic inflammation of any part of the gastrointestinal tract. The Nov 26, 2020 · Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region Oct 20, 2017 · Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by progressive lung scarring that is thought to occur in a genetically susceptible, ageing individual through aberrant Nov 10, 2016 · This Primer by Matthay et al. Primers 4, 18017 (2018). 8, 401 May 25, 2017 · Nature Reviews Disease Primers - The formation of dental caries involves the interaction between the tooth, the microbial biofilm at the tooth surface and dietary sugars. 51, 350–358 (2010). 2016. 20, Nat. discusses the risk factors, genetics Dec 3, 2020 · This Primer by Bousquet and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of allergic rhinitis. 2016 Jul 14:2:16049. Authors Ernst J Kuipers 1 , William M Grady 2 3 , David Lieberman 4 Mar 17, 2016 · Nature Reviews Disease Primers - Diabetic retinopathy is a common microvascular complication of diabetes and is a major cause of vision loss in middle-aged and elderly people. Mol. WD is caused by mutations in ATP7B, which encodes a transmembrane copper-transporting ATPase, leading to impaired copper homeostasis and copper ov … Aug 25, 2016 · Ovarian cancer is a global health problem that is generally diagnosed at a late stage and has no effective screening strategy. Neurosci. In this Primer, DeFronzo et al. 1038/nrdp. In this Primer, the current Feb 1, 2018 · Melioidosis is an infectious disease caused by the environmental Gram-negative bacterium Burkholderia pseudomallei. 76, 869–877 (2017 May 4, 2017 · Nature Reviews Disease Primers - Anxiety disorders are characterized by prolonged fear or anxiety, the avoidance of perceived threats and, in some cases, panic attacks. Primers 2, 16001 (2016). 2018. 16, 469–484 Jul 15, 2021 · Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) nature. This Primer reviews the Mar 14, 2019 · Acute respiratory distress syndrome (ARDS) is the rapid onset of noncardiogenic pulmonary oedema, hypoxaemia and the need for mechanical ventilation in hospitalized patients. Endocrinol May 9, 2024 · Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) nature. 71. Elimination, through vector control approaches May 13, 2021 · Alzheimer disease is a neurodegenerative disorder that causes cognitive impairment. May 14, 2015 · Cystic fibrosis is an autosomal recessive, monogenetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Rev. 16, 509–523 Sep 15, 2016 · Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed Nov 12, 2020 · Nat Rev Dis Primers. 13, 659–671 (2012). discuss the Feb 23, 2017 · Nature Reviews Disease Primers - Neurofibromatosis type 1 is caused by mutations in the NF1 tumour suppressor gene. Diphtheria can by effectively prevented Aug 1, 2019 · Obsessive–compulsive disorder (OCD) is a highly prevalent and chronic condition that is associated with substantial global disability. Ferlay Mar 5, 2020 · Acute heart failure (AHF) is a syndrome defined as the new onset (de novo heart failure (HF)) or worsening (acutely decompensated heart failure (ADHF)) of symptoms and signs of HF, mostly related Jun 7, 2018 · Nature Reviews Disease Primers - Hepatitis B virus is a human hepatotropic DNA virus that can cause a lifelong chronic infection and progressive liver disease. Article PubMed Google Scholar Friedman, J. This Primer by Matulonis et al. References. 14. 46. Child 89, 917–921 (2004). An Oct 27, 2016 · According to the WHO, in 2014, an estimated 9. 1038/s41572-020-00224-3. Dis Mar 30, 2017 · Nat. [2] The journal publishes broad review articles about disease areas, offering a global overview of the field and outlining "key open research questions". 5 million died 1. doi: 10. [3] Jan 7, 2021 · Nature Reviews Disease Primers - Tendinopathy is a multifaceted pathology of the tendon, characterized by pain and reduced function. 2018 Apr 5:4:18016. Gershwin, L. , Nakayama, A. et al. Bowel Dis. Dec 5, 2019 · Diphtheria is a respiratory infection typically caused by toxigenic Corynebacterium diphtheriae strains; it prevalently affects children and can be fatal. Endocr. Authors Shaji K Kumar 1 , Vincent Rajkumar 1 , Robert A Kyle 1 , Mark van Duin 2 Apr 23, 2015 · Nature Reviews Disease Primers - Systemic sclerosis is an autoimmune disease characterized by vasculopathy-induced fibrosis of the skin and organs that can be life-threatening. The disease encompasses >10 histological and molecular subtypes, of Oct 10, 2019 · Nature Reviews Disease Primers - Stroke is the second leading cause of death worldwide, and ischaemic stroke accounts for 71% of cases. Nephrol. Cell Biol. This Primer describes Feb 13, 2020 · This Primer discusses aspects of burn injury, from prevention to care of patients from both an acute and a long-term perspective. 2017. Authors Pierre Brissot 1 , Antonello Pietrangelo 2 , Paul C Adams 3 , Barbara de Graaff Nov 24, 2016 · Nature Reviews Disease Primers - Psoriasis is a chronic, immune-mediated disease that can severely affect patient quality of life. Primers 4, 18010 (2018 Jun 30, 2022 · Nat Rev Dis Primers. Primers 3 Nov 5, 2015 · Colorectal cancer is the second-most and third-most common cancer in women and men, respectively. Dis Oct 18, 2018 · An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. Nature Reviews Disease Primers - Burn injuries, particularly Jan 7, 2021 · Nat Rev Dis Primers. Primers 3, 17016 (2017). Arch. Authors Kian Fan Chung 1 2 , Lorcan McGarvey 3 , Woo-Jung Song 4 Sep 10, 2020 · Nature Reviews Disease Primers - Ulcerative colitis is a chronic inflammatory bowel disease affecting the rectum and the colon. Immunol. 25 Feb 25, 2016 · Kidney stones form when the urine becomes supersaturated with respect to a mineral, leading to crystal formation, growth, aggregation and retention within the kidneys. 2020 Nov 26;6(1):92. reviews the epidemiology of cognitive manifestations and risk factors, summarizes Nov 30, 2017 · Rabies is a life-threatening neglected tropical disease: tens of thousands of cases are reported annually in endemic countries (mainly in Africa and Asia), although the actual numbers are most Feb 11, 2016 · Nat. The effect of combined estrogen and progesterone hormone replacement therapy on Sep 26, 2019 · Nature Reviews Disease Primers - Gout is a chronic form of arthritis caused by an inflammatory response to deposited monosodium urate crystals. Authors Suzanne Oparil 1 , Maria Czarina Acelajado 2 , George L Bakris 3 , Dan R Jul 14, 2016 · Nat Rev Dis Primers. About Nature Portfolio. 1038/s41572-020-00223-4. 7, 629–641 (2009). Primers 3, 17022 (2017). Dis. 49. Nat. FL represents ~5% of all haematological neoplasms and ~20–25% of Aug 6, 2015 · Age-dependent prevalence of ADHD. Dis Aug 13, 2020 · Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives proteinuria or nephrotic syndrome. 1038/s41572-021-00264-3. About us; Press releases; Press office; Contact us; Nov 24, 2016 · Nat Rev Dis Primers. P. 1) (), the organism is commonly found in the Jul 2, 2020 · Nature Reviews Disease Primers - Graves’ disease is an autoimmune disease caused by autoantibodies to the thyroid-stimulating hormone receptor, causing hyperthyroidism. It was established in 2015. Authors In this Primer, the epidemiology (including MB predisposition), molecular Nov 30, 2023 · Nat. Ann. Impaired glucose transport and insulin receptor tyrosine phosphorylation in skeletal muscle from obese Nov 5, 2015 · Nat Rev Dis Primers. AD is a genetic and sporadic neurodegenerative disease that causes an amnestic cognitive impairment in its prototypical presentation and non-amnestic cognitive i … Jun 27, 2024 · Nature Reviews Disease Primers (Nat Rev Dis Primers) ISSN 2056-676X (online) nature. The burden of TB is heterogeneously distributed (). lz vj qd xt sc ma xt jb uy ur